Mouse IL-10 Secretion Assay – Cell Enrichment and Detection Kit (PE)

Mouse IL-10 Secretion Assay – Cell Enrichment and Detection Kit (PE)

The Mouse IL-10 Secretion Assay - Cell Enrichment and Detection Kit was developed for the sensitive detection and the enrichment of murine IL-10-secreting cells.

Background information

Interleukin-10 (IL-10) is predominantly secreted by CD4
+
T cells and antigen-presenting cells, such as monocytes/macrophages and dendritic cells. IL-10 has important suppressive functions on immune responses and is involved in the maintenance of tolerance. IL-10 blocks activation of cytokine synthesis by T
H
1 cells, activated monocytes, and NK cells. It can stimulate the immunoglobulin production by B cells.

Downstream applications

The Mouse IL-10 Secretion Assay was used for the analysis of the sequential production of cytokines by T helper lymphocytes.
1
The assay was also used for analysis of IL-10 expression by T
H
2 cells.
2
It has also been used to analyze secretion of IL-10 by dendritic cells from mouse spleen
3
and by T cells from bronchioalveolar lavages
4
.

Columns

MS, LS, or autoMACS
®
Columns.
Product options: 1

Product information

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Price

Mouse IL-10 Secretion Assay – Cell Enrichment and Detection Kit (PE)

  • For research use only
for 50
tests
(1)
130-090-490
-

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