CD45RA MicroBeads, rat

CD45RA MicroBeads, rat

Rat CD45RA MicroBeads were developed for positive selection or depletion of B cells from blood, peripheral lymphoid organs, or from non-lymphoid tissues.

Background information

The CD45RA isoform is B cell lineage–specific. It is neither expressed on thymocytes nor on any peripheral T cell subset. CD45RA was not detected on B cell progenitors in bone marrow.

Downstream applications

B cells separated with CD45RA MicroBeads can be used for analysis of B cell migration into non-lymphoid organs after infections, for evaluation of B cell responses after allograft transplantation, or to study the role of B cells in autoimmune diseases, such as arthritis or diabetes. Isolated B cells were used for adoptive transfer experiments to study autoimmunity and tolerance induction after xenogeneic thymus transplantation.
1
Furthermore, isolated B cells were used for molecular analysis.
2

Columns

For positive selection: MS, LS, XS, or autoMACS
®
Columns. For depletion: LD, D, or autoMACS Columns.
  • Selected references

    1. Yan, Y. et al. (2003) Pathogenesis of autoimmunity after xenogeneic thymus transplantation. J. Immunol. 170: 5936-5946
    2. Lombardi, M. S. et al. (2001) Adjuvant arthritis induces down-regulation of G protein-coupled receptor kinases in the immune system. J. Immunol. 166: 1635-1640
Product options: 1
130-090-494

CD45RA MicroBeads, rat

for 1×
10
9
total cells
-