CD19 MicroBeads, mouse

CD19 MicroBeads, mouse

CD19 MicroBeads were developed for the positive selection or depletion of mouse B cells from peripheral blood and various tissues such as bone marrow, lymph nodes, and spleen.

Background information

CD19 is expressed on B lineage cells throughout their development from the early pro-B cell stages onwards and is down-regulated upon terminal differentiation to plasma cells.

Downstream applications

B cells isolated with CD19 MicroBeads were used to study the accessibility of enhancer elements during B cell development by
in vivo
footprinting.
1
Cell extracts prepared from purified B cells were used to analyze conditions for V(D)J recombination in a cell-free system.
2
Furthermore, mRNA was isolated from selected B cells for microarray analyses to quantify transcription factor expression during B cell development.
3

Columns

For positive selection: MS, LS, XS, or autoMACS
®
Columns. For depletion: LD, CS, D, or autoMACS Columns.
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