iPS-Brew GMP Medium

iPS-Brew GMP Medium is a xeno-and serum-free medium formulation that has been developed for the maintenance of undifferentiated pluripotent stem cells under feeder-free conditions. The complete medium is composed of the specifically formulated “iPS-Brew GMP Basal Medium” as well as the optimized “iPS-Brew GMP Supplement R” that when used together support long-term growth and maintenance of undifferentiated cells.
Recombinant human TGF-β1 has to be added to the complete medium for the maintenance and expansion of human pluripotent stem cells.


MACS GMP Products are for research use and
ex vivo
cell culture processing only, and are not intended for human
in vivo
applications. For regulatory status in the USA, please contact your local representative.

Background information

iPS-Brew GMP Medium is based on the formulation of StemMACS iPS-Brew XF (#130-104-368) thus enabling seamless translation from research to clinical applications.
  • Serum-free and xeno-free formulation
  • Manufactured under strictly controlled conditions
  • Consistent lot-to-lot performance
  • Quality control: functionality test on every batch
  • 500 mL bottles – without phenol red
  • Recombinant human TGF- ß1 has to be added to the medium


iPS-Brew GMP Medium has been developed for the maintenance and expansion of human pluripotent stem cells on standard cell attachment matrices, e.g. Laminin 521.

Quality statement

MACS GMP Products are manufactured and tested under a quality management system (ISO 13485) and are in compliance with relevant GMP guidelines. They are designed following the recommendations of USP <1043> on ancillary materials.
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