CD8 antibodies

CD8 antibodies

Clone: BW135/80
BW135/80 recognizes the human CD8 antigen which is strongly expressed on human cytotoxic T cells and thymocytes, and is also expressed on a subset of NK cells. The CD8 antigen is a disulfide-linked dimer that exists either as a CD8α homodimer or as a CD8α/β heterodimer. CD8 acts as a coreceptor for the T cell receptor and binds to the MHC Class I molecule. The CD8 antibody recognizes the α-subunit of the antigen.

Applications

Reagent can be used for immunophenotyping by flow cytometry. Abnormal numbers of cells expressing this antigen or aberrant expression levels of the antigen can be expected in some disease states. It is important to understand the normal expression pattern for this antigen and its relationship to expression of other relevant antigens in order to perform appropriate analysis.
Expression of CD8 may be used as aid to diagnostic in the characterization of samples from individuals suspected with hematologic neoplasia.

Alternative Names

Leu-2, Ly-2, T8

Technical specifications

  • Antigen: CD8
  • Clone: BW135/80
  • Isotype: mouse IgG2a
  • Alternative names of antigen: Leu-2, Ly-2, T8
  • Molecular mass of antigen [kDa]: 45
  • Distribution of antigen: dendritic cells, NK cells, red blood cells, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, APC-Vio770
  • Brochures and posters

  • Certificates of Analysis (CoA)

    Please follow this
    link
    to search for certificates by lot number.
Product options: 2

Product information

Size
Order no.
Price

CD8-FITC

  • BW135/80
  • CE–IVD
for 100
tests
170-078-007
-

CD8-APC-Vio770

  • BW135/80
  • CE–IVD
for 100
tests
170-080-010
-