CD64 antibodies

CD64 antibodies

Clone: 10.1.1
10.1.1 recognizes human CD64, a high affinity Fc receptor for IgG. CD64 contains three Ig-like domains in its extracellular domain and binds both monomeric and aggregated IgG and contributes to antibody-dependent cellular cytotoxicity (ADCC), phagocytosis, and the clearance of immune complexes. It is constitutively expressed on macrophages, monocytes, and eosinophils and can be up-regulated on neutrophils during infection or after stimulation with IFN-γ and colony-stimulating factors G-CSF and GM-CSF.

Applications

Reagent can be used for immunophenotyping by flow cytometry. Abnormal numbers of cells expressing this antigen or aberrant expression levels of the antigen can be expected in some disease states. It is important to understand the normal expression pattern for this antigen and its relationship to expression of other relevant antigens in order to perform appropriate analysis.
Expression of CD64 may be used as aid to diagnostic in the characterization of samples from individuals suspected with hematologic neoplasia.

Technical specifications

  • Antigen: CD64
  • Clone: 10.1.1
  • Isotype: mouse IgG1κ
  • Molecular mass of antigen [kDa]: 41
  • Distribution of antigen: dendritic cells, eosinophils, macrophages, monocytes, myeloid cells, neutrophils
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE
  • Certificates of Analysis (CoA)

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Product information

Size
Order no.
Price

CD64-PE

  • 10.1.1
  • CE–IVD
for 100
tests
170-078-085
-