CD33 antibodies

CD33 antibodies

Clone: AC104.3E3
AC104.3E3 recognizes the human CD33 antigen, a 67 kDa glycoprotein belonging to the sialoadhesin superfamily. The CD33 antigen is highly expressed on human monocytes but weakly on granulocytes and some – but not all – myeloid dendritic cells. The CD33 antigen is also found on myeloid progenitor cells (CFU-GEMM, CFU GM, CFU-G, BFU-E) but is not expressed on lymphocytes, platelets, erythrocytes, or primitive hematopoietic stem cells.

Applications

Reagent can be used for immunophenotyping by flow cytometry. Abnormal numbers of cells expressing this antigen or aberrant expression levels of the antigen can be expected in some disease states. It is important to understand the normal expression pattern for this antigen and its relationship to expression of other relevant antigens in order to perform appropriate analysis.
Expression of CD33 may be used as aid to diagnostic in the characterization of samples from individuals suspected with hematologic neoplasia.

Alternative Names

My9, p67, Siglec-3

Technical specifications

  • Antigen: CD33
  • Clone: AC104.3E3
  • Isotype: mouse IgG1
  • Alternative names of antigen: My9, p67, Siglec-3
  • Molecular mass of antigen [kDa]: 38
  • Distribution of antigen: basophils, dendritic cells, granulocytes, Langerhans cells, leukemia cells, macrophages, mast cells, monocytes, myeloid cells, NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC
  • Certificates of Analysis (CoA)

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Product options: 2

Product information

Size
Order no.
Price

CD33-PE

  • AC104.3E3
  • CE–IVD
for 100
tests
170-078-025
-

CD33-APC

  • AC104.3E3
  • CE–IVD
for 100
tests
170-078-026
-