CD23 antibodies

CD23 antibodies

Clone: M-L23.4
M-L23.4 recognizes human CD23, a 45 kDa type II transmembrane glycoprotein that belongs to the immunoglobulin family. It is expressed on most mature B cells, monocytes, follicular dendritic cells, and at low levels on T cells, Langerhans cells, eosinophils, and platelets. CD23 is thought to play a role in the regulation of B cell activation and IgE response. It is up-regulated upon B cell activation. The proteolytic cleavage of membrane CD23 can result in the release of soluble forms of the antigen (sCD23) with a reported biological activity.

Applications

Reagent can be used for immunophenotyping by flow cytometry. Abnormal numbers of cells expressing this antigen or aberrant expression levels of the antigen can be expected in some disease states. It is important to understand the normal expression pattern for this antigen and its relationship to expression of other relevant antigens in order to perform appropriate analysis.
Expression of CD23 may be used as aid to diagnostic in the characterization of samples from

Alternative Names

BLAST-2, FcεRII

Technical specifications

  • Antigen: CD23
  • Clone: M-L23.4
  • Isotype: mouse IgG1
  • Alternative names of antigen: BLAST-2, FcεRII
  • Molecular mass of antigen [kDa]: 8
  • Distribution of antigen: B cells, dendritic cells, endothelial cells, eosinophils, Langerhans cells, macrophages, monocytes, neutrophils, NK cells, platelets, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC
  • Certificates of Analysis (CoA)

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Product information

Size
Order no.
Price

CD23-FITC

  • M-L23.4
  • CE–IVD
for 100
tests
170-078-020
-