Anti-TCRα/β antibodies

Anti-TCRα/β antibodies

Clone: BW242/412
BW242/412 recognizes the human α/β T cell receptor (TCR). The T cell receptor (TCR) is a heterodimer composed of two transmembrane glycoprotein chains, α and β. Both chains are members of the Ig superfamily and consist of a constant and a polymorphic variable region. The variable region of the TCRα/β is involved in recognition of antigenic peptides presented by the MHC complex of antigen-presenting cells. The Anti-TCRα/β antibody, BW242/412, recognizes a common determinant of the TCRα/β-CD3 complex.

Applications

Reagent can be used for immunophenotyping by flow cytometry. Abnormal numbers of cells expressing this antigen or aberrant expression levels of the antigen can be expected in some disease states. It is important to understand the normal expression pattern for this antigen and its relationship to expression of other relevant antigens in order to perform appropriate analysis. Expression of TCRα/β may be used as aid to diagnostic in the characterization of samples from individuals suspected with hematologic neoplasia.

Technical specifications

  • Antigen: TCRα/β
  • Clone: BW242/412
  • Isotype: mouse IgG2b
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC
Product options: 2

Product information

Size
Order no.
Price

Anti-TCRα/β-PE

  • BW242/412
  • CE–IVD
for 100
tests
170-078-046
-

Anti-TCRα/β-APC

  • BW242/412
  • CE–IVD
for 100
tests
170-078-047
-