CD327 (Siglec-6) antibodies, human

CD327 (Siglec-6) antibodies, human

Clone: REA852 | Dilution: 1:50
Clone REA852 recognizes the human CD327 antigen, which is also known as sialic acid binding Ig-like lectin 6 (Siglec-6), belonging to the Ig superfamily that is involved in cell-cell interactions and signaling. As an adhesion molecule, CD327 mediates sialic acid dependent interaction to cells by binding to the alpha-2,6-linked sialic acid and is highly expressed in placenta and at low levels in spleen, peripheral blood leukocytes, and small intestine.
Additional information: Clone REA852 displays negligible binding to Fc receptors.

Alternative names

CD33 antigen-like 1, CDw327, Obesity-binding protein 1, Siglec-6

Technical specifications

  • Antigen: CD327 (Siglec-6)
  • Clone: REA852
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CD33 antigen-like 1, CDw327, Obesity-binding protein 1, Siglec-6
  • Entrez Gene ID: 946
  • Molecular mass of antigen [kDa]: 47
  • Distribution of antigen: placenta, spleen, leukocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Biotin
  • Selected references

    1. Powell, L. D. et al. (1995) I-type lectins. J. Biol. Chem. 270(24): 14243-14246
    2. Patel, N. et al. (1999) OB-BP1/Siglec-6. a leptin- and sialic acid-binding protein of the immunoglobulin superfamily. J. Biol. Chem. 274(32): 22729-22738
    3. Crocker, P. R. et al. (2002) New I-type lectins of the CD 33-related siglec subgroup identified through genomics. Biochem. Soc. Symp. (69): 83-94
Product options: 8
130-112-898

CD327 (Siglec-6)-FITC, human

for 30
tests
(1)
SGD 210.00
130-112-709

CD327 (Siglec-6)-FITC, human

for 100
tests
(1)
SGD 500.00
130-112-899

CD327 (Siglec-6)-PE, human

for 30
tests
(1)
SGD 250.00
130-112-710

CD327 (Siglec-6)-PE, human

for 100
tests
(1)
SGD 590.00
130-112-900

CD327 (Siglec-6)-APC, human

for 30
tests
(1)
SGD 250.00
130-112-711

CD327 (Siglec-6)-APC, human

for 100
tests
(1)
SGD 590.00
130-112-897

CD327 (Siglec-6)-Biotin, human

for 30
tests
(1)
SGD 210.00
130-112-708

CD327 (Siglec-6)-Biotin, human

for 100
tests
(1)
SGD 500.00