CD310 (VEGFR-3) antibodies, mouse

CD310 (VEGFR-3) antibodies, mouse

Clone: REA834 | Dilution: 1:50
Clone REA843 recognizes the mouse CD310 antigen, a member of the receptor tyrosine kinase family. This 195 kDa molecule is also known as Flt-4 or VEGFR-3. During early embryogenesis all endothelial cells express CD310, while in the adult tissues CD310 expression disappears from the vascular endothelial cells and is observed only on the lymphatic endothelium. CD310 expression is also induced upon tumor angiogenesis. VEGF-C and VEGF-D are ligands for CD310.
Additional information: Clone REA834 displays negligible binding to Fc receptors.

Alternative names

FLT4, Chy, FLT-4, VEGFR-3

Technical specifications

  • Antigen: CD310 (VEGFR-3)
  • Clone: REA834
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: FLT4, Chy, FLT-4, VEGFR-3
  • Entrez Gene ID: 14257
  • Molecular mass of antigen [kDa]: 151
  • Distribution of antigen: endothelial cells, tumor cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, Biotin
  • Selected references

    1. Galland, F. et al. (1992) Chromosomal localization of FLT4, a novel receptor-type tyrosine kinase gene. Genomics 13(2): 475-478
    2. Kubo, H. et al. (2000) Involvement of vascular endothelial growth factor receptor-3 in maintance of integrity of endothelial cell lining during tumor angiogenesis. Blood 2(96): 546-553
    3. Zhang, L. et al. (2010) VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesis. Cell Res. 20(12): 1319-1331
Product options: 10
130-112-774

CD310 (VEGFR-3)-FITC, mouse

30 µg in 200 µL (1)
SGD 120.00
130-112-585

CD310 (VEGFR-3)-FITC, mouse

150 µg in 1 mL (1)
SGD 340.00
130-112-772

CD310 (VEGFR-3)-PE, mouse

30 µg in 200 µL (1)
SGD 195.00
130-112-583

CD310 (VEGFR-3)-PE, mouse

150 µg in 1 mL (1)
SGD 580.00
130-112-773

CD310 (VEGFR-3)-APC, mouse

30 µg in 200 µL (1)
SGD 195.00
130-112-584

CD310 (VEGFR-3)-APC, mouse

150 µg in 1 mL (1)
SGD 580.00
130-112-770

CD310 (VEGFR-3)-PE-Vio615, mouse

30 µg in 200 µL (1)
SGD 225.00
130-112-581

CD310 (VEGFR-3)-PE-Vio615, mouse

150 µg in 1 mL (1)
SGD 645.00
130-112-775

CD310 (VEGFR-3)-Biotin, mouse

30 µg in 200 µL (1)
SGD 120.00
130-112-586

CD310 (VEGFR-3)-Biotin, mouse

150 µg in 1 mL (1)
SGD 340.00