CD2 antibodies, human

CD2 antibodies, human

Clone: REA972 | Dilution: 1:50
Clone REA972 recognizes the human CD2 antigen, a 50 kDa single-chain transmembrane glycoprotein also known as LFA-2 or receptor for sheep erythrocytes. CD2 functions as a costimulatory molecule on T and natural killer (NK) cells and is a receptor for other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3/CD58). It belongs to the Ig superfamily and is involved in cell signaling and lymphocyte adhesion. The CD2 antibody reacts with 80–90% of peripheral blood lymphocytes and more than 95% of thymocytes and recognizes all T cells and a subset of NK cells.
Additional information: Clone REA972 displays negligible binding to Fc receptors.

Alternative names

LFA-2, SRBC-R, T11, SRBC

Technical specifications

  • Antigen: CD2
  • Clone: REA972
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: LFA-2, SRBC-R, T11, SRBC
  • Entrez Gene ID: 914
  • Molecular mass of antigen [kDa]: 37
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    chimpanzee (
    Pan troglodytes
    )
    ,
    squirrel monkey (
    Saimiri sciureus
    )
  • Distribution of antigen: B cells, lymphocytes, macrophages, mast cells, NK cells, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, APC-Vio770
  • Selected references

    1. Sanchez-Madrid, F. et al. (1982) Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc. Natl. Acad. Sci. U.S.A. 79: 7489-7493
    2. Ozwara, H. et al. (1997)
      Flow cytometric analysis on reactivity of human T lymphocyte-specific and cytokine-receptor-specific antibodies with peripheral blood mononuclear cells of chimpanzee (
      Pan troglodytes
      ), rhesus macaque (
      Macacca mulatta
      ) and squirrel monkey (
      Saimiri sciureus
      ).
      J. Med. Primatol. 26(3): 164-171
Product options: 12
130-116-251

CD2-FITC, human

for 30
tests
(1)
SGD 195.00
130-116-148

CD2-FITC, human

for 100
tests
(1)
SGD 485.00
130-116-252

CD2-PE, human

for 30
tests
(1)
SGD 235.00
130-116-149

CD2-PE, human

for 100
tests
(1)
SGD 580.00
130-116-253

CD2-APC, human

for 30
tests
(1)
SGD 235.00
130-116-150

CD2-APC, human

for 100
tests
(1)
SGD 580.00
130-116-260

CD2-PE-Vio615, human

for 30
tests
(1)
SGD 265.00
130-116-157

CD2-PE-Vio615, human

for 100
tests
(1)
SGD 630.00
130-116-254

CD2-PE-Vio770, human

for 30
tests
(1)
SGD 265.00
130-116-151

CD2-PE-Vio770, human

for 100
tests
(1)
SGD 630.00
130-116-255

CD2-APC-Vio770, human

for 30
tests
(1)
SGD 265.00
130-116-152

CD2-APC-Vio770, human

for 100
tests
(1)
SGD 630.00