Anti-SSEA-4 antibodies, human

Anti-SSEA-4 antibodies, human

Clone: REA101 | Dilution: 1:11
Clone REA101 recognizes the glycolipid carbohydrate epitope stage specific embryonic antigen 4 (SSEA-4). SSEA-4 is found on undifferentiated human embryonic stem (ES) cells, induced pluripotent (iPS) cells, embryonal carcinoma (EC) cells, as well as embryonic germ (EG) cells and a variety of somatic stem cells, such as dental pulp stem cells, umbilical cord blood–derived very small embryonic like stem cells (VSELs), and mesenchymal stromal cells.
Additional information: Clone REA101 displays negligible binding to Fc receptors.

Technical specifications

  • Antigen: SSEA-4
  • Clone: REA101
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Cross-reactivity: mouse, rabbit, canine, chicken
  • Distribution of antigen: ES and iPS cells, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, VioBlue, VioGreen, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin, FITC
  • Selected references

    1. Aloia, A. et al. (2015) The sialyl-glycolipid stage-specific embryonic antigen 4 marks a subpopulation of chemotherapy-resistant breast cancer cells with mesenchymal features. Breast Cancer Res. 17: 146
    2. Gang, E. J. et al. (2007) SSEA-4 identifies mesenchymal stem cells from bone marrow. Blood 109(4): 1743-1751
    3. Truong, T. T. et al. (2011) SSEA4 is a potential negative marker for the enrichment of human corneal epithelial stem/progenitor cells. Invest. Ophthalmol. Vis. Sci. 52(9): 6315-6320
    4. Kannagi, R. et al. (1983) Stage-specific embryonic antigens (SSEA-3 and -4) are epitopes of a unique globo-series ganglioside EMBO J. 2(12): 2355-2361
  • Customer reports and application notes

Product options: 13
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SGD 630.00
for 30
tests
(1)
SGD 265.00
for 100
tests
(1)
SGD 630.00
for 30
tests
(1)
SGD 265.00
for 100
tests
(1)
SGD 630.00
for 100
tests
(1)
SGD 485.00

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