Anti-Cytokeratin 8 antibodies, human

Anti-Cytokeratin 8 antibodies, human

Clone: REA885 | Dilution: 1:50
Clone REA885 recognizes the human type II keratin protein cytokeratin 8, an intermediate filament protein, which is found in epithelial and carcinoma cells. In adult tissues cytokeratin 8 is expressed as a heterodimer with cytokeratin 18.
Keratins play a critical role in mechanical stability and integrity of epithelial cells and tissues, have regulatory functions, and are involved in intracellular signaling pathways.
Additional information: Clone REA885 displays negligible binding to Fc receptors.

Alternative names

Cytokeratin-8, CK-8, Keratin-8

Technical specifications

  • Antigen: Cytokeratin 8
  • Clone: REA885
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: Cytokeratin-8, CK-8, Keratin-8
  • Entrez Gene ID: 3856
  • Molecular mass of antigen [kDa]: 54
  • Distribution of antigen: epithelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC
  • Selected references

    1. Leube, R. E. et al. (1986)
      Cytokeratin expression in simple epithelia. III. Detection of mRNAs encoding human cytokeratins nos. 8 and 18 in normal and tumor cells by hybridization with cDNA sequences
      in vitro
      and
      in situ
      .
      Differentiation 33(1): 69-85
    2. Krauss, S. et al. (1990) Organization and sequence of the human gene encoding cytokeratin 8. Gene 86(2): 241-249
    3. Moll, R. et al. (2008) The human keratins: biology and pathology. Histochem. Cell Biol. 129(6): 705-733
Product options: 6
130-114-646

Anti-Cytokeratin 8-FITC, human

for 30
tests
(1)
SGD 210.00
130-114-455

Anti-Cytokeratin 8-FITC, human

for 100
tests
(1)
SGD 500.00
130-114-647

Anti-Cytokeratin 8-PE, human

for 30
tests
(1)
SGD 250.00
130-114-456

Anti-Cytokeratin 8-PE, human

for 100
tests
(1)
SGD 590.00
130-114-648

Anti-Cytokeratin 8-APC, human

for 30
tests
(1)
SGD 250.00
130-114-457

Anti-Cytokeratin 8-APC, human

for 100
tests
(1)
SGD 590.00