REAlease® CD5 Complexes, mouse

CD5 Complexes
, mouse

Clone: REAL174 | Dilution: 1:50
Clone REAL174 is an antibody fragment derived from the full CD5 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.
Clone REAL174 recognizes the mouse CD5 antigen, a 67 kDa single-pass type I membrane protein which is also known as lymphocyte antigen 1 (Ly-1). CD5 is expressed by a majority of thymocytes, mature T cells, and a subset of B cells. The expression of CD5 by a small B cell subset characterizes a developmentally and functionally distinct lineage of B cells called B-1a cells. CD5 plays a role in the interaction of T and B cells and is a counter-receptor for CD72.
The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

Alternative names

Ly-1, Ly-12, Ly-A, Lyt-1, T1, Tp67

Technical specifications

  • Antigen: CD5
  • Clone: REAL174
  • Isotype control: REAL Control
  • Alternative names of antigen: Ly-1, Ly-12, Ly-A, Lyt-1, T1, Tp67
  • Distribution of antigen: thymocytes, T cells, B cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioGreen, PE
  • Selected references

    1. Tarakhovsky, A. et al. (1995) A role for CD5 in TCR-mediated signal transduction and thymocyte selection. Science 269(5223): 535-537
    2. Efanov, A. et al. (2010)
      leukemic cell populations in TCL1 transgenic mice show significantly increased proliferation and Akt phosphorylation.
      Leukemia 24(5): 970-975
    3. Lundy, S. K. et al. (2014)
      Characterization and activity of Fas ligand producing CD5
      B cells.
      Methods Mol. Biol. 1190: 81-102
Product options: 4
30 µg in 200 µL (1)
SEK 1 010,00 
30 µg in 200 µL (1)
SEK 1 200,00 
for 100
SEK 1 575,00 
for 100
SEK 1 765,00 

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