CD28 antibodies, human

CD28 antibodies, human

Clone: REA612
Clone REA612 recognizes the human CD28 antigen, a type I transmembrane protein, which is highly expressed on CD3
thymocytes, most peripheral thymocytes, and plasma cells but not in less mature B cells. Binding of CD28 to its ligands CD80 or CD86 costimulates T cell effector function and T cell–dependent antibody production
in vitro
in vivo
. In the presence of antibodies directed against CD2 and CD3, CD28 antibodies stimulate T cell proliferation and cytokine production.
Additional information: Clone REA612 displays negligible binding to Fc receptors.

Alternative names

T44, Tp44

Technical specifications

  • Antigen: CD28
  • Clone: REA612
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: T44, Tp44
  • Entrez Gene ID: 940
  • Molecular mass of antigen [kDa]: 23
  • Distribution of antigen: B cells, lymphocytes, plasma cells, T cells, thymocytes
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
Product options: 1

CD28 pure, human

100 µg in 100 µL
SEK 1 730,00