Science Jobs at Miltenyi Biotec

With more than 20 years of experience we are pioneering cellular immunotherapy. We are enabling and developing innovative and promising cellular immunotherapy approaches for cancer and degenerative diseases. 

Covering the whole process from basic research, technologies and applications to therapies we do research in the fields of neoantigens and tumor infiltrating lymphocytes and investigate the tumor microenvironment and its escape mechanisms. Your research can help us to understand underlying mechanisms and turn this knowledge into therapies. 

With a strong focus on CAR technology we want to create an innovation pipeline of new CAR technologies, targets and therapies, improve the safety and efficacy of our CAR T cell pharmaceutical and bring the design and manufacturing of CAR T cells to the next level. Hence, we constantly strive to develop new approaches for gene engineering, gene delivery, cell processing and more, and to embed our knowledge in our CliniMACS Prodigy platform for fully automated and scalable cell manufacturing procedures. 

With your agile mind and scientific curiosity you can support us in gaining more knowledge about cellular immunotherapies, improving existing therapy concepts and rolling out those concepts for different kind of tumors. Add in your self-motivated and eager-to-learn personality and let your work really make a difference. 

This research field is the initiator of a great venture and Miltenyi Biotec contributes by establishing new concepts and tools to turn stem cells into relevant therapeutic candidates for cellular therapies for a wide range of common diseases without existing cures such as Parkinson’s, diabetes, chronic heart failure and retinal disease. 

To enable a successful clinical translation many questions need to be resolved and obstacles overcome. Hence, one of our biggest challenges is to develop a meaningful and cost effective manufacturing concept. 

A highly motivated and skilled team with a broad range of expertise welcomes every new and enquiring mind in this rapidly advancing and fascinating field of research. 

Your passion and curiosity for science are enabling the next wave of Miltenyi Biotec´s success stories.  

Nowadays there is barely an experiment running that does not use recombinant proteins. Miltenyi Biotec is an expert in this field. For over 20 years now, we have been producing recombinant proteins for research and clinical use, developing them from cloning to expression, from purification to characterization.  

As each protein is different, we use a variety of methods and state-of-the art devices. We continuously develop and establish new methods and technologies. With the protein being of use in almost every Miltenyi Group development project, as a member of this team you are connected throughout the entire R&D department and beyond.  

CAR binders, CAR detection reagents based on recombinant antigens, and MACS GMP cytokines for the culture of CAR T and CAR NK cells are just the most obvious contributions this team makes to our mission “make cancer history”. If you are up to big challenges, like the balancing act between highest product quality and shortest development times, and are looking for anything but a run-of-the-mill routine, a dynamic and open minded team will welcome you and your ideas and offer you the room to develop into a leading expert. 

With today´s progress in science and cutting edge technology, research projects create huge amounts of data that can only help changing lives when analyzed correctly. Our Bioinformatics Team deals with the implementations for big data, the development of data analysis methods and software for life science and clinical data. This includes cutting edge methods like machine learning, data quality control systems, statistical analysis pipelines, data visualization and data handling to answer questions that ultimately contribute towards the development of new therapeutics.  

The different types of data including various -omics data, complex images, flow cytometry data, produced in-house and in collaboration with other scientists and clinicians.. Data analyses by our bioinformaticians represent a crucial puzzle piece in our mission “make cancer history” as they are able to provide a more comprehensive picture of disease and help us to stratify patients in order to suggest personalized therapies. 

Join a team of biologists, bioinformaticians and computer scientists that celebrates the team’s diversity and uniqueness and bring your own ideas to the table. 

In our chemical biology department we develop tools and kits for researchers to isolate and analyze their target cell population.  

The very core of almost every technology developed by Miltenyi Biotec is antibodies that are linked to fluorochromes, magnetic beads, enzymes and more. Our researchers are dedicated to optimizing all these different types of antibody-conjugates, to finding new ways to synthesize novel and brighter fluorochromes, to developing new buffers and accessories for our technologies and and to bringing our bead-based technologies to the next level. Their aim is to provide solutions and optimized workflows for our customers in academia, industry and health care institutions. 

Here chemists and biologists work hand in hand and complement each other with their expertise in highly interdisciplinary project teams to work on cutting edge technology and clinical applications. Join us to link chemistry and biology to make cancer history.  

Using our expertise in cell analysis we are entering the field of in vitro diagnostics (IVD). Beside the growing number of antibodies that we are offering for diagnostic purposes, our researchers are continually developing new approaches to IVDs that contribute to the big picture “make cancer history”.  

IVDs are an important part of the workflow Miltenyi Biotec provides in the area of cell and gene therapy. Our researchers focus on assays for assessment of the quality of the cellular product before administration and the immunomonitoring of patients after the cell product has been administered. Covering assays for bench to bedside and bedside to bench applications, you will develop reagents and tools for scientists working in a highly regulated environment in which these quality control and monitoring assays are crucial for a successful therapy.  Hence, as one of the researchers in this division you are not just an expert in the lab, you also need to know how to address all the regulatory requirements that need to be met. 

You are at the interface of research and clinical applications, and the best reward for your hard work is to see the actual lives your developments might change.  

Isolating your targets cells or preparing your samples is always just the first step of your experiment. What follows is the analysis of your cell population or tissue section. Our researchers develop new procedures and optimize existing methods for carrying out these analyses. Whether by microscopy or by flow cytometry or by cell sorting their accuracy is in paramount. 

We are developing novel products for sample preparation of tissues and organoids that will support lightsheet microscopy. Our goal is to gain a very detailed characterization of tissue structures in 3D and thereby learn more about antigen distribution in whole tissues. Furthermore, we use our MACSima imaging platform to perform simultaneous analysis of multiple markers on the same tissue structure. This helps scientists  visualize the heterogeneity of marker expression in tumor tissue, which is crucial for developing novel cancer treatment strategies.  

Next to imaging techniques, flow cytometry is an important analysis tool and one of our key competences. Our scientists develop and improve applications, hardware and software for everything from basic research to diagnostics for certain cancers, such as leukemia and lymphoma.  

Join our team of interdisciplinary scientists and make valuable contributions to our cell analysis portfolio that enables scientists worldwide to carry out groundbreaking research. 

We at Miltenyi Biotec reckon that good research starts with happy cells. That might sound easy but it’s anything but trivial. The preparation of cells, e.g., from a tissue to a single cell suspension, the isolation of a specific cell type, and the cultivation of those cells belong to Miltenyi Biotec´s core business areas with 30 years of experience … but we aren’t stopping there. 

Because we want our customers to achieve the best possible experimental conditions for their work, we need your support in developing new instruments, consumables, reagents and automated solutions to improve lab workflows worldwide. Miltenyi Biotec offers complete solutions: once the cell is isolated we provide the matching media, growth factors and much more. 

Tumor tissue can be especially challenging. Engineers and scientists at Miltenyi Biotec are working on new dissociation techniques for fresh and fixed tumor tissue that are prerequisite for successful downstream applications. 

Finding the optimal compromise between efficient tissue dissociation and epitope recovery for antigen binding is one of our main goals. Join us in enabling and optimizing cancer research and help make cancer history.