Specifications for MHC Class II (I-Ek) Antibody, anti-mouse/rat, REAfinity™
Overview
Clone REA510 recognizes the mouse MHC class II alloantigen I-Ek. It also recognizes the rat MHC class II antigen RT1D and cells from mice of the H-2
d, H-2
p, and H-2
r haplotypes. Cells from mice of the H-2
b, H-2
f, H-2
g7, H-2
q, and H-2
s haplotypes do not express the I-E antigen. MHC class II is expressed on antigen-presenting cells, such as dendritic cells, monocytes, macrophages, B cells in lymphoid and non-lymphoid tissue, thymic epithelial cells, and on subsets of hematopoietic progenitor cells in the bone marrow.
Additional information: Clone REA510 displays negligible binding to Fc receptors.
Alternative names
RT1DDetailed product information
Technical specifications
| Clone | REA510 |
|---|
| Clonality | monoclonal |
|---|
| Isotype | recombinant human IgG1 |
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| Isotype control | REA Control Antibody, human IgG1 |
|---|
| Host | human cell line |
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| Type of antibody | Primary antibodies, Recombinant antibodies |
|---|
| Species | mouse, rat |
|---|
| Antigen | MHC Class II (I-Ek) |
|---|
| Alternative names of antigen | RT1D |
|---|
| Molecular mass of antigen [kDa] | 27(same molecular weight for human and mouse/rat) |
|---|
| Distribution of antigen | B cells, dendritic cells, macrophages, monocytes, epithelial cells, hematopoietic stem and progenitor cells |
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| Entrez Gene ID | 14969, 294270 |
|---|
| RRID | AB_2652883, AB_2652884, AB_2652885, AB_2652886, AB_2652887, AB_2652888, AB_2652889, AB_2652890, AB_2652891, AB_2652892, AB_2652893, AB_2652894, AB_2652895, AB_2652896, AB_2652897, AB_2652898, AB_2652899, AB_2652900, AB_2652901, AB_2921997, AB_2652882 |
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