Background information
The CD25 antibody (clone 3G10) recognizes a 55 kDa glycoprotein also known as the low-affinity interleukin-2 receptor alpha chain (IL-2Rα). This molecule reveals three epitope regions: A, B, and C. Clone 3G10 recognizes epitope region A.
The CD25 antigen is expressed on activated T and B cells, on macrophages, and on a subset of non-activated CD4-positive regulatory T cells.
Applications
MACS GMP CD25 Fluorescent Antibodies are for identification of CD25 positive cells by flow cytometry as well as cell enrichment by flow cytometric sorting. MACS GMP CD25-PE-Biotin can furthermore be used for a magnetic pre-enrichment step using the CliniMACS Anti-Bioin Product Line.
Quality statement
MACS GMP Products are manufactured and tested under a quality management system (ISO 13485) and are in compliance with relevant GMP guidelines. They are designed following the recommendations of USP <1043> on ancillary materials.
