REAlease® CD180 (RP105) Complexes, human

REAlease
®
CD180 (RP105) Complexes
, human

Clone: REAL445 | Dilution: 1:50
Clone REAL445 is an antibody fragment derived from the full CD180 (RP105) antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.
Clone REAL445 recognizes the human CD180 antigen, also known as RP105, which is a 105 kDa type 1 transmembrane protein of the toll-like receptor (TLR) family. The extracellular domain of CD180 is associated with MD-1, which forms the cell surface complex RP105/MD-1. Together with TLR4, it mediates B cell recognition and signaling of LPS. RP105 is expressed on mature B cells in mantle zones as well as on monocytes, macrophages, and dendritic cells.
The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

Alternative names

LY64, Ly78, RP105

Technical specifications

  • Antigen: CD180 (RP105)
  • Clone: REAL445
  • Isotype control: REAL Control
  • Alternative names of antigen: LY64, Ly78, RP105
  • Distribution of antigen: B cells, dendritic cells, monocytes, macrophages, plasma cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE
Product options: 2
for 30
tests
(1)
EUR  134,00
for 100
tests
(1)
EUR  330,00