CD7 antibodies, human

CD7 antibodies, human

Clone: CD7-6B7 | Dilution: 1:50
Clone CD7-6B7 recognizes the human CD7 antigen, a single-pass type I membrane protein also known as leu-9 or GP40. CD7 appears early in T cell ontogeny and is expressed by most T cells in the periphery. It is also found on natural killer (NK) cells, hematopoietic progenitors, monocytes, acute lymphocytic leukemia, and some acute myeloid leukemia cells. Although the ligand is yet not identified, CD7 has been recognized as a costimulatory molecule. CD7 activates phosphatidylinositol 3-kinase which is involved in CD7-mediated regulation of integrin adhesiveness. Furthermore, it has been reported that the β-galactoside-binding lectin galectin-1 binds CD7, leading to induction of apoptosis of thymocytes and T cells, with implications for certain autoimmune diseases and T cell lymphomas.

Alternative names

GP40, Leu-9, TP41, Tp40

Technical specifications

  • Antigen: CD7
  • Clone: CD7-6B7
  • Isotype: mouse IgG2aκ
  • Isotype control: Mouse IgG2a – isotype control antibodies
  • Alternative names of antigen: GP40, Leu-9, TP41, Tp40
  • Entrez Gene ID: 924
  • Molecular mass of antigen [kDa]: 23
  • Distribution of antigen: T cells, NK cells, monocytes, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC-Vio770, PE, APC, Biotin, VioBright FITC
  • Selected references

Product options: 10
for 30
tests
(1)
EUR  124,00
for 100
tests
(1)
EUR  299,00
130-123-308

CD7-PE, human

for 30
tests
(1)
EUR  113,00
130-123-247

CD7-PE, human

for 100
tests
(1)
EUR  273,00
130-123-326

CD7-APC, human

for 30
tests
(1)
EUR  113,00
130-123-265

CD7-APC, human

for 100
tests
(1)
EUR  273,00
for 30
tests
(1)
EUR  93,00
for 100
tests
(1)
EUR  227,00
for 30
tests
(1)
EUR  124,00
for 100
tests
(1)
EUR  299,00

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