CD68 antibodies, mouse

Clone: FA-11 | Dilution: 1:10
The monoclonal antibody FA-11 recognizes mouse CD68, also known as macrosialin, which is a heavily glycosylated type I transmembrane protein of the LAMP (lysosomal-associated membrane protein) family. It is expressed on tissue macrophages, langerhans cells and at a low density on dendritic cells. Murine CD68 is predominantly intracellular but it is reported that 10-15% of CD68 is expressed on the cell surface as well. Macrosialin functions as a macrophage receptor for oxidized low density lipoprotein.

Alternative names

Lamp4, SCARD1, gp110, macrosialin

Technical specifications

  • Antigen: CD68
  • Clone: FA-11
  • Isotype: rat IgG2a
  • Isotype control: Rat IgG2a – isotype control antibodies
  • Alternative names of antigen: Lamp4, SCARD1, gp110, macrosialin
  • Entrez Gene ID: 12514
  • Molecular mass of antigen [kDa]: 33
  • Distribution of antigen: macrophages, dendritic cells, Langerhans cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio770, PerCP-Vio700, Biotin, pure
  • Selected references

    1. Ramprasad, M. P. et al. (1996) Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein. Proc. Natl. Acad. Sci. U.S.A. 93: 14833-14838
    2. Kurushima, H. et al. (2000) Surface expression and rapid internalization of macrosialin (mouse CD68) on elicited mouse peritoneal macrophages. J. Leukoc. Biol. 67: 104-108
    3. Smith, M. J. et al. (1987) Differential expression of murine macrophage surface glycoprotein antigens in intracellular membranes. J. Cell. Sci. 87: 113-119
    4. Jungblut, M. et al. (2012) Isolation and characterization of living primary astroglial cells using the new GLAST-specific monoclonal antibody ACSA-1. Glia 60(6): 894-907
    5. G. Kantzer, C. et al. (2017) Anti-ACSA-2 defines a novel monoclonal antibody for prospective isolation of living neonatal and adult astrocytes. Glia 65(6): 990-1004
    6. Batiuk, M. Y. et al. (2017) An immunoaffinity-based method for isolating ultrapure adult astrocytes based on ATP1B2 targeting by the ACSA-2 antibody. J. Biol. Chem. 292(21): 8874-8891
Product options: 17
130-102-920

CD68-FITC, mouse

9 µg in 300 µL (1)
EUR  21,00
130-102-534

CD68-FITC, mouse

30 µg in 1 mL (1)
EUR  36,00
130-102-923

CD68-PE, mouse

9 µg in 300 µL (1)
EUR  28,00
130-102-614

CD68-PE, mouse

30 µg in 1 mL (1)
EUR  62,00
130-102-918

CD68-APC, mouse

9 µg in 300 µL (1)
EUR  45,00
130-102-585

CD68-APC, mouse

30 µg in 1 mL (1)
EUR  62,00
9 µg in 300 µL (1)
EUR  59,00
30 µg in 1 mL (1)
EUR  98,00
9 µg in 300 µL (1)
EUR  61,00
30 µg in 1 mL (1)
EUR  98,00
9 µg in 300 µL (1)
EUR  45,00
30 µg in 1 mL (1)
EUR  103,00
9 µg in 300 µL (1)
EUR  56,00
30 µg in 1 mL (1)
EUR  103,00
9 µg in 300 µL (1)
EUR  15,00
30 µg in 1 mL (1)
EUR  36,00
130-115-808

CD68 pure, mouse

100 µg in 1 mL
EUR  360,00

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