CD4 antibodies, human

Clone: REA623 | Dilution: 1:50
Clone REA623 recognizes the human CD4 antigen, a 55 kDa single-pass type I membrane protein, also known as T4/Leu-3. CD4 is highly expressed on T helper cells and at a lower level on monocytes and dendritic cells. It is involved in the recognition of MHC class II/peptide complexes by the TCR heterodimers and is the receptor for the human immunodeficiency virus (HIV).
Additional information: Clone REA623 displays negligible binding to Fc receptors.

Alternative names

T4, Leu-3, CD4mut

Technical specifications

  • Antigen: CD4
  • Clone: REA623
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: T4, Leu-3, CD4mut
  • Entrez Gene ID: 920
  • Molecular mass of antigen [kDa]: 48
  • Distribution of antigen: monocytes, T cells, thymocytes, T helper cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, Vio515, VioBright 515, Vio667, VioBright 667, Biotin, FITC, VioBright FITC, PE, APC, VioBlue, VioGreen
  • Selected references

    1. Tebas, P. et al. (2014) Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV. N. Engl. J. Med. 370(10): 901-910
    2. Maddon, P. J. et al. (1985) The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family. Cell 42(1): 93-104
    3. Barclay, A. N. et al. (1993) CD4 and the immunoglobulin superfamily. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 342(1299): 7-12
Product options: 31
130-114-722

CD4-FITC, human

for 30
tests
(1)
EUR  72,00
130-114-531

CD4-FITC, human

for 100
tests
(1)
EUR  180,00
130-114-585

CD4-FITC, human

for 500
tests
(1)
EUR  453,00
for 30
tests
(1)
EUR  124,00
for 100
tests
(1)
EUR  299,00
130-113-787

CD4-PE, human

for 30
tests
(1)
EUR  98,00
130-113-225

CD4-PE, human

for 100
tests
(1)
EUR  242,00
130-113-784

CD4-APC, human

for 30
tests
(1)
EUR  98,00
130-113-222

CD4-APC, human

for 100
tests
(1)
EUR  242,00
for 30
tests
(1)
EUR  118,00
for 100
tests
(1)
EUR  283,00
for 30
tests
(1)
EUR  118,00
for 100
tests
(1)
EUR  283,00
for 30
tests
(1)
EUR  124,00
for 100
tests
(1)
EUR  299,00
for 30
tests
(1)
EUR  124,00
for 100
tests
(1)
EUR  299,00
for 30
tests
(1)
EUR  124,00
for 100
tests
(1)
EUR  299,00
for 30
tests
(1)
EUR  124,00
for 100
tests
(1)
EUR  299,00
for 30
tests
(1)
EUR  118,00
for 100
tests
(1)
EUR  283,00
for 30
tests
(1)
EUR  155,00
for 100
tests
(1)
EUR  371,00
for 30
tests
(1)
EUR  118,00
for 100
tests
(1)
EUR  283,00
for 30
tests
(1)
EUR  155,00
for 100
tests
(1)
EUR  371,00
for 30
tests
(1)
EUR  72,00
for 100
tests
(1)
EUR  180,00

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