CD355 (CRTAM) antibodies, human

CD355 (CRTAM) antibodies, human

Clone: REA1225 | Dilution: 1:50
Clone REA1225 recognizes the human CD355 protein, a class I–restricted T cell–associated molecule (CRTAM). It is expressed on activated class I MHC restricted T cells, including CD8
+
T cells and NKT cells and binds nectin-like protein 2 (NecI2). The binding of CRTAM and NecI2 triggers cytotoxity of NK cells and IFN-γ secretion by CD8
+
T cells.
Additional information: Clone REA1225 displays negligible binding to Fc receptors.

Alternative names

CRTAM

Technical specifications

  • Antigen: CD355 (CRTAM)
  • Clone: REA1225
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CRTAM
  • Entrez Gene ID: 56253
  • Molecular mass of antigen [kDa]: 43
  • Distribution of antigen: T cells, NKT cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio615, VioBright 515, Biotin
  • Selected references

    1. Boles, K. S. et al. (2005)
      The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8
      +
      T-cell responses through the cell-surface receptor CRTAM.
      Blood 106: 779-786
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