CD3 antibodies, mouse

CD3 antibodies, mouse

Clone: REA641 | Dilution: 1:10
Clone REA641 recognizes the mouse CD3 complex, which is expressed on all mature T lymphocytes, NKT cells, and during the development of thymocytes. CD3, also known as T3, belongs to the Ig superfamily. It consists of CD3ε, δ, γ, and ζ chains and forms a TCR complex by associating with TCR α/β or γ/δ chains. The TCR does not possess intracellular signaling domains, uncoupling Ag recognition from T cell signaling. The TCR is instead non-covalently associated with a multisubunit signaling apparatus, consisting of the CD3εγ and CD3εδ heterodimers and the CD3ζζ homodimer, which collectively form the TCR-CD3 complex. CD3 is involved in T cell activation, signal transduction, and antigen recognition by binding the peptide/MHC antigen complex.
Additional information: Clone REA641 displays negligible binding to Fc receptors.

Alternative names

T cell antigen receptor complex, T3, AI504783, CD3epsilon, T3E, Ctg-3, Ctg3, T3g

Technical specifications

  • Antigen: CD3
  • Clone: REA641
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: T cell antigen receptor complex, T3, AI504783, CD3epsilon, T3E, Ctg-3, Ctg3, T3g
  • Entrez Gene ID: 12501, 12502
  • Molecular mass of antigen [kDa]: 37
  • Distribution of antigen: NKT cells, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: Biotin, PE
Product options: 2
9 µg in 300 µL (1)
EUR  21,00
30 µg in 1 mL (1)
EUR  36,00

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