CD25 antibodies, human

CD25 antibodies, human

Clone: REA570 | Dilution: 1:50
Clone REA570 recognizes the human CD25 glycoprotein, also known as the low-affinity interleukin-2 receptor alpha chain (IL-2Rα). It associates with IL-2 receptor β (CD122) and γ chains (CD132) to form a high affinity IL-2R complex. CD25 is expressed on activated T and B cells, on macrophages, and on a subset of non-activated CD4
+
regulatory T cells. Clone REA570 recognizes epitope region A.
Additional information: Clone REA570 displays negligible binding to Fc receptors

Alternative names

IL2RA, IDDM10, IL2R, TCGFR, p55, Tac

Technical specifications

  • Antigen: CD25
  • Clone: REA570
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: IL2RA, IDDM10, IL2R, TCGFR, p55, Tac
  • Entrez Gene ID: 3559
  • Molecular mass of antigen [kDa]: 55
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    olive baboon (
    Papio anubis
    )
  • Distribution of antigen: T cells, B cells, macrophages
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, VioBright 515, Biotin
  • Selected references

    1. Lee, S. H. et al. (2012) Cutting edge: a novel mechanism bridging innate and adaptive immunity: IL-12 induction of CD25 to form high-affinity IL-2 receptors on NK cells. J. Immunol. 189(6): 2712-2716
    2. Piccirillo, C. A. et al. (2006)
      Development and function of naturally occurring CD4
      +
      CD25
      +
      regulatory T cells.
      J. Leukoc. Biol. 3: 458-470
    3. Goudy, K. et al. (2013) Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity. Clin. Immunol. 146(3): 248-261
Product options: 10
130-113-848

CD25-PE, human

for 30
tests
(1)
EUR  95,00
130-113-286

CD25-PE, human

for 100
tests
(1)
EUR  235,00
130-113-846

CD25-APC, human

for 30
tests
(1)
EUR  95,00
130-113-284

CD25-APC, human

for 100
tests
(1)
EUR  235,00
for 30
tests
(1)
EUR  120,00
for 100
tests
(1)
EUR  290,00
for 30
tests
(1)
EUR  150,00
for 100
tests
(1)
EUR  360,00
for 30
tests
(1)
EUR  70,00
for 100
tests
(1)
EUR  175,00

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