CD20 antibodies, human

CD20 antibodies, human

Clone: LT20 | Dilution: 1:50
The antibody recognizes the CD20 antigen, a non-glycosylated transmembrane protein of 33–37 kDa that is expressed on B lineage cells from the pre–B cell stage to the B cell lymphoblast stage. The antigen is further expressed on most malignant B cells. CD20 is not found on early B cell progenitors or plasma cells. Oligomers of CD20 form a Ca
2+
channel and might function in the regulation of local responses during B cell activation.

Alternative names

MS4A1, B1, Bp35, CVID5, LEU-16, MS4A2, S7, Ly-44

Technical specifications

  • Antigen: CD20
  • Clone: LT20
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: MS4A1, B1, Bp35, CVID5, LEU-16, MS4A2, S7, Ly-44
  • Entrez Gene ID: 931
  • Molecular mass of antigen [kDa]: 33
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: B cells, cancer stem cells, dendritic cells, lymphocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PerCP, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin, PE-Vio615
  • Selected references

    1. Lamprecht, B. et al. (2008) Aberrant expression of the Tʜ2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3alpha. Blood 112(8): 3339-3347
    2. Maxwell, S. A. et al. (2009) 14-3-3zeta J. Biol. Chem. 284(33): 22379-22389
    3. Countouriotis, T. B. et al. (2002) Cell surface antigen and molecular targeting in the treatment of hematologic malignancies. Stem Cells 20(3): 215-229
    4. Cragg, M. S. et al. (2002)
      Opposing properties of CD20 mAb; in: Mason, D.
      et al.
      (eds.): Leucocyte typing VII,
      Oxford, Oxford University Press
    5. Polyak, M. J. and Deans, J. P. (2002)
      CD20 Workshop Panel report: in Mason, D.
      et al.
      (eds.): Leucocyte typing VII,
      Oxford, Oxford University Press
Product options: 22
130-113-935

CD20-FITC, human

for 30
tests
(1)
EUR  93,00
130-113-373

CD20-FITC, human

for 100
tests
(1)
EUR  227,00
130-113-936

CD20-PE, human

for 30
tests
(1)
EUR  113,00
130-113-374

CD20-PE, human

for 100
tests
(1)
EUR  273,00
130-113-932

CD20-APC, human

for 30
tests
(1)
EUR  113,00
130-113-370

CD20-APC, human

for 100
tests
(1)
EUR  273,00
for 30
tests
(1)
EUR  118,00
for 100
tests
(1)
EUR  283,00
for 30
tests
(1)
EUR  118,00
for 100
tests
(1)
EUR  283,00
for 30
tests
(1)
EUR  113,00
for 100
tests
(1)
EUR  273,00
for 30
tests
(1)
EUR  124,00
for 100
tests
(1)
EUR  299,00
for 30
tests
(1)
EUR  124,00
for 100
tests
(1)
EUR  299,00
for 30
tests
(1)
EUR  124,00
for 100
tests
(1)
EUR  299,00
for 30
tests
(1)
EUR  93,00
for 100
tests
(1)
EUR  227,00
for 30
tests
(1)
EUR  124,00
for 100
tests
(1)
EUR  299,00

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