CD127 antibodies, human

CD127 antibodies, human

Clone: MB15-18C9 | Dilution: 1:11
Clone MB15-18C9 recognizes the CD127 antigen, which is the α-chain of the interleukin 7 (IL-7) receptor, a type I membrane glycoprotein. Signaling of IL-7 through the IL-7R requires both IL-7Rα and the common cytokine gamma chain (γc). CD127 can be identified on immature B cells through the early pre–B stage, on thymocytes, and on most mature T cells with transient down-regulation upon activation. On regulatory T cells CD127 is absent and its expression is inversely correlated with FoxP3 expression and suppressive function. CD127 is also used by thymic stromal derived lymphopoietin (TSLP) as part of a complex.

Alternative names

IL-7R, IL-7Rα, CDW127, ILRA

Technical specifications

  • Antigen: CD127
  • Clone: MB15-18C9
  • Isotype: mouse IgG2aκ
  • Isotype control: Mouse IgG2a – isotype control antibodies
  • Alternative names of antigen: IL-7R, IL-7Rα, CDW127, ILRA
  • Entrez Gene ID: 3575
  • Molecular mass of antigen [kDa]: 49
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    cynomolgus monkey (
    Macaca fascicularis
  • Distribution of antigen: B cells, bone marrow, liver, lymphocytes, monocytes, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure, PE
  • Selected references

    1. Sudo, T. et al. (1993) Expression and function of the interleukin 7 receptor in murine lymphocytes. Proc. Natl. Acad. Sci. U.S.A. 90: 9125-9129
Product options: 1
100 µg in 1 mL
EUR  203,00

Related products

4 products available