Anti-IFN-γ antibodies, human

Anti-IFN-γ antibodies, human

Clone: REA600 | Dilution: 1:50
Clone REA600 recognizes the human interferon gamma (IFN-γ) antigen, a cytokine of type II class interferons. IFN-γ is produced by lymphocytes that are involved in inflammatory immune responses. It functions as a potent activator of macrophages, increases the antiviral and antitumor effects of the type I interferons, and has antiproliferative effects on transformed cells. IFN-γ is predominantly released by memory and effector CD4
+
and CD8
+
T cells as well as by NK cells upon activation.
Additional information: Clone REA600 displays negligible binding to Fc receptors.

Alternative names

IFN-gamma, Immune interferon

Technical specifications

  • Antigen: IFN-γ
  • Clone: REA600
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: IFN-gamma, Immune interferon
  • Entrez Gene ID: 3458
  • Molecular mass of antigen [kDa]: 16
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    chimpanzee (
    Pan troglodytes
    )
    , baboon,
    pigtail monkey (
    Macaca nemestrina
    )
    ,
    african green monkey (
    Chlorocebus aethiops
    )
    ,
    sooty mangabey (
    Cercocebus atys
    )
  • Distribution of antigen: macrophages, T cells, NK cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, VioBlue
  • Selected references

    1. Gray, P. W. et al. (1982) Structure of the human immune interferon gene. Nature 298(5877): 859-863
    2. Green, J. A. et al. (1969) Immune specific induction of interferon production in cultures of human blood lymphocytes. Science 164(3886): 1415-1417
    3. Schoenborn, J. R. et al. (2007) Regulation of interferon-gamma during innate and adaptive immune responses. Adv. Immunol. 96: 41-101
Product options: 12
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(1)
EUR  93,00
for 100
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for 30
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EUR  113,00
for 100
tests
(1)
EUR  273,00
for 30
tests
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EUR  113,00
for 100
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EUR  273,00
for 30
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EUR  124,00
for 100
tests
(1)
EUR  299,00
for 30
tests
(1)
EUR  124,00
for 100
tests
(1)
EUR  299,00
for 30
tests
(1)
EUR  118,00
for 100
tests
(1)
EUR  283,00

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