Anti-HLA-G antibodies - functional grade, human

Anti-HLA-G antibodies - functional grade, human

Clone: 87G
Clone 87G recognizes the human HLA-G antigen, a heterodimeric class I molecule consisting of a heavy chain and a light chain.The heavy chain is approximately 45 kDa and is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. Clone 87G reacts with isoforms of HLA-G1 and HLA-G5.

Applications

This pure – functional grade antibody is suited for cell culture functional assays, for example, blocking of receptor-ligand binding.

Alternative names

HLA G antigen, MHC class I antigen G

Technical specifications

  • Antigen: HLA-G
  • Clone: 87G
  • Isotype: mouse IgG2aκ
  • Alternative names of antigen: HLA G antigen, MHC class I antigen G
  • Entrez Gene ID: 3135
  • Molecular mass of antigen [kDa]: 36
  • Distribution of antigen: placenta
  • Endotoxin level: Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
  • Selected references

    1. Odum, N. et al. (1991) Homotypic aggregation of human cell lines by HLA class II-, class Ia- and HLA-G-specific monoclonal antibodies. Eur. J. Immunol. 21(9): 2121-2131
    2. Rutten, M. J. et al. (2014) HLA-G expression is an independent predictor for improved survival in high grade ovarian carcinomas. J Immunol Res
    3. Jiang, F. et al. (2015) Role of HLA-G1 in trophoblast cell proliferation, adhesion and invasion. Biochem. Biophys. Res. Commun. 458(1): 154-160
Product options: 1
500 µg in 0.5 mL
EUR  330,00

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