Anti-ESAM antibodies, mouse

Anti-ESAM antibodies, mouse

Clone: REA722 | Dilution: 1:50
Clone REA722 recognizes the mouse endothelial cell-selective adhesion molecule (ESAM) antigen, a 55 kDa molecule, which is also known as a transmembrane tight junction protein composed of a single transmembrane domain and a cytoplasmic domain. By affecting endothelial cell contacts, ESAM is mostly expressed on endothelial cells of various organs such as heart, lung, kidney, and skin, participating in the migration of neutrophils through the vessel wall.
Additional information: Clone REA722 displays negligible binding to Fc receptors.

Alternative names

Endothelial cell-selective adhesion molecule, ESAM1

Technical specifications

  • Antigen: ESAM
  • Clone: REA722
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Endothelial cell-selective adhesion molecule, ESAM1
  • Entrez Gene ID: 69524
  • Molecular mass of antigen [kDa]: 39
  • Distribution of antigen: heart, kidney, skin, lung
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Hirata, K. et al. (2001) Cloning of an immunoglobulin family adhesion molecule selectively expressed by endothelial cells. J. Biol. Chem. 276(19): 16223-16231
    2. Nasdala, I. et al. (2002) A transmembrane tight junction protein selectively expressed on endothelial cells and platelets. J. Biol. Chem. 277(18): 16294-16303
    3. Wegmann, F. et al. (2004) Endothelial adhesion molecule ESAM binds directly to the multidomain adaptor MAGI-1 and recruits it to cell contacts. Exp. Cell Res. 300(1): 121-133
Product options: 12
30 µg in 200 µL (1)
EUR  100,00
150 µg in 1 mL (1)
EUR  295,00
30 µg in 200 µL (1)
EUR  80,00
150 µg in 1 mL (1)
EUR  230,00
30 µg in 200 µL (1)
EUR  80,00
150 µg in 1 mL (1)
EUR  230,00
30 µg in 200 µL (1)
EUR  100,00
150 µg in 1 mL (1)
EUR  295,00
30 µg in 200 µL (1)
EUR  100,00
150 µg in 1 mL (1)
EUR  295,00
30 µg in 200 µL (1)
EUR  40,00
150 µg in 1 mL (1)
EUR  120,00

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