StemMACS™ RepSox

StemMACS™ RepSox

StemMACS™ RepSox is a small molecule inhibitor of the TGFβ type I receptor ALK5.

Background information

StemMACS™ RepSox is an inhibitor of the TGF-β type I receptor ALK5. RepSox prevents autophosphorylation of the ALK5 receptor
1
. It has been shown to promote reprogramming efficiency by replacing Sox2 and inducing Nanog.
  • Selected references

    1. Gellibert, F. et al. (2004) Identification of 1,5-naphthyridine derivatives as a novel series of potent and selective TGF-beta type I receptor inhibitors. J. Med. Chem. 47: 4494-4506
Product options: 1
130-117-340

StemMACS RepSox

10 mg
EUR  177,00