Type of antibody:
Primary antibodies, Recombinant antibodies
recombinant human IgG1
Alternative names:
IL17E, Interleukin 17E, IL-25, IL25, Interleukin 25

Specifications for IL-17E Antibody, anti-mouse, REAfinity™


Clone REA952 recognizes the mouse interleukin 17E (IL-17E) antigen. IL-17 is a family of pro-inflammatory cytokines that plays a central role in adaptive immunity as well as autoinflammatory disorders. Data from several mouse models suggest that IL-17 plays a key role in the host defense against certain extracellular bacterial infections. IL-17E is suggested to be an important mediator of allergic disease via production of IL-4, IL-5, IL-13, and eotaxin. IL-17E expression is found in low levels in different peripheral tissues, e.g., prostate, testis, trachea, brain, kidney, and lung.
Additional information: Clone REA952 displays negligible binding to Fc receptors.

Alternative names

IL17E, Interleukin 17E, IL-25, IL25, Interleukin 25

Detailed product information

Technical specifications

Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Alternative names of antigenIL17E, Interleukin 17E, IL-25, IL25, Interleukin 25
Molecular mass of antigen [kDa]18
Distribution of antigenbrain, testicle, kidney, lung, prostate
Entrez Gene ID140806
RRIDAB_2727179, AB_2727178, AB_2727201, AB_2727180, AB_2727200, AB_2727199

Resources for IL-17E Antibody, anti-mouse, REAfinity™


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References for IL-17E Antibody, anti-mouse, REAfinity™


  1. Fort, M. M. et al. (2001)
    IL-25 induces IL-4, IL-5, and IL-13 and Tʜ2-associated pathologies
    in vivo
    Immunity 15(6): 985-995
  2. Hurst, S. D. et al. (2002)
    New IL-17 family members promote Tʜ1 or Tʜ2 responses in the lung:
    in vivo
    function of the novel cytokine IL-25.
    J. Immunol. 169(1): 443-453
  3. Weaver, C. T. et al. (2007) IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu. Rev. Immunol. 25: 821-852

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