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FR10-11G9 recognizes human CD26, a costimulatory molecule that is involved in T cell activation. CD26 is a type II transmembrane protein that acts as an ectoenzyme with prolyl oligopeptidase activity. It is widely expressed in various tissues. In the immune system CD26 is expressed on thymocytes, activated T cells, B cells, NK cells, and macrophages.
Detailed product information
Technical specifications
Clone
FR10-11G9
Isotype
mouse IgG2aκ
Type of antibody
Primary antibodies
Species
human
Antigen
CD26
Molecular mass of antigen [kDa]
88
Distribution of antigen
epithelial cells, macrophages, monocytes, NK cells, T cells, stem cells, leukocytes, cancer stem cells, thymocytes
to search for Certificates of Analysis (CoA) by lot number.
References for CD26 antibodies
Publications
Stelzer, G. T. et al. (1997) U.S.-Canadian consensus recommendations on the immunophenotypic analysis of hematologic neoplasia by flow cytometry: standardization and validation of laboratory procedures. Cytometry 30(5): 214-230
De Meester, I. et al. (1999) CD26, let it cut or cut it down. Immunol. Today 20: 367-375
Reinhold, D. et al. (2002) The role of dipeptidyl peptidase IV (DP IV) enzymatic activity in T cell activation and autoimmunity. J. Biol. Chem. 383(7-8): 1133-1138
Rothe, G et al. (2012) Consensus protocol for the flow cytometric Immunophenotyping of hematopoietic malignancies. Leukemia 10(5): 877-895
van Dongen, J. J. M. et al. (2012) EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes. Leukemia 26(9): 1908-1975
Clinical and Laboratory Standards Institute (CLSI) (2007) Clinical Flow Cytometric Analysis of Neoplastic Hematolympoid Cells, CLSI document H43-A2 (ISBN 1-56238-635-2). CLSI; Approved Guideline - Second Edition
Clinical and Laboratory Standards Institute (CLSI) (2007) Enumeration of immunologically defined cell populations by flow cytometry, CLSI document H42-A2 (ISBN 1-56238-640-9). CLSI; Approved Guideline - Second Edition
FR10-11G9 recognizes human CD26, a costimulatory molecule that is involved in T cell activation. CD26 is a type II transmembrane protein that acts as an ectoenzyme with prolyl oligopeptidase activity. It is widely expressed in various tissues. In the immune system CD26 is expressed on thymocytes, activated T cells, B cells, NK cells, and macrophages.
Detailed product information
Technical specifications
Clone
FR10-11G9
Isotype
mouse IgG2aκ
Type of antibody
Primary antibodies
Species
human
Antigen
CD26
Molecular mass of antigen [kDa]
88
Distribution of antigen
epithelial cells, macrophages, monocytes, NK cells, T cells, stem cells, leukocytes, cancer stem cells, thymocytes
Stelzer, G. T. et al. (1997) U.S.-Canadian consensus recommendations on the immunophenotypic analysis of hematologic neoplasia by flow cytometry: standardization and validation of laboratory procedures. Cytometry 30(5): 214-230
De Meester, I. et al. (1999) CD26, let it cut or cut it down. Immunol. Today 20: 367-375
Reinhold, D. et al. (2002) The role of dipeptidyl peptidase IV (DP IV) enzymatic activity in T cell activation and autoimmunity. J. Biol. Chem. 383(7-8): 1133-1138
Rothe, G et al. (2012) Consensus protocol for the flow cytometric Immunophenotyping of hematopoietic malignancies. Leukemia 10(5): 877-895
van Dongen, J. J. M. et al. (2012) EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes. Leukemia 26(9): 1908-1975
Clinical and Laboratory Standards Institute (CLSI) (2007) Clinical Flow Cytometric Analysis of Neoplastic Hematolympoid Cells, CLSI document H43-A2 (ISBN 1-56238-635-2). CLSI; Approved Guideline - Second Edition
Clinical and Laboratory Standards Institute (CLSI) (2007) Enumeration of immunologically defined cell populations by flow cytometry, CLSI document H42-A2 (ISBN 1-56238-640-9). CLSI; Approved Guideline - Second Edition
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