Clone:
M-L23.4
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ, mouse IgG1
Applications:
FC, MICS, IF, IHC, MC
Alternative names:
FCER2, BLAST-2, CD23A, CLEC4J, FCE2, IGEBF, FcεRII

Extended validation for CD23 Antibody, anti-human

Specificity

Epitope competition
In order to compare the epitope specificity of an antibody, the clone being used is compared with other known clones recognizing the same antigen in a competition assay.
Other clonesOverlap in epitope recognition with M-L23.4
REA1222++
EVCV-5+
EBCV-2+
M-L233+
9P25+
Cells were incubated with an excess of purified unconjugated CD23 (M-L23.4) antibody followed by staining with fluorochrome-conjugated antibodies of other known clones against the same marker. Based on the fluorescence signal obtained, the clones were identified as recognizing completely overlapping (++), partially overlapping (+), or completely different epitopes (-) of the marker.

Specifications for CD23 Antibody, anti-human

Overview

CD23 is a 45 kDa type II transmembrane glycoprotein that belongs to the immunoglobulin family. It is expressed on most mature B cells, monocytes, follicular dendritic cells, and at low levels on T cells, Langerhans cells, eosinophils, and platelets. CD23 is thought to play a role in the regulation of B cell activation and IgE response. It is up-regulated upon B cell activation. The proteolytic cleavage of membrane CD23 can result in the release of soluble forms of the antigen (sCD23) with a reported biological activity.

Alternative names

FCER2, BLAST-2, CD23A, CLEC4J, FCE2, IGEBF, FcεRII

Detailed product information

Technical specifications

CloneM-L23.4
Clonalitymonoclonal
Isotypemouse IgG1κ, mouse IgG1
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD23
Alternative names of antigenFCER2, BLAST-2, CD23A, CLEC4J, FCE2, IGEBF, FcεRII
Molecular mass of antigen [kDa]36
Distribution of antigenB cells, dendritic cells, endothelial cells, Langerhans cells, macrophages, monocytes, NK cells, platelets, T cells, eosinophils, neutrophils, thymocytes
Entrez Gene ID2208
RRIDAB_2751599, AB_2857651, AB_2857623, AB_2819599, AB_2819584, AB_2659801, AB_2659799, AB_2659800, AB_10828801, AB_2751645

Resources for CD23 Antibody, anti-human

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

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