CD140b Antibody, anti-mouse, REAfinity™
Clone:
REA634
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC
Alternative names:
PDGF-R-beta, PDGFR-beta, PDGFR-1

Specifications for CD140b Antibody, anti-mouse, REAfinity™

Overview

Clone REA634 recognizes the mouse CD140b antigen, also known as platelet-derived growth factor receptor-β (PDGFR-β), a tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB. CD140b plays a role in the regulation of embryonic development, cell proliferation, differentiation, chemotaxis, survival, and migration. CD140b is expressed on embryonic tissues and mesenchymal-derived cells in adult mice.
Additional information: Clone REA634 displays negligible binding to Fc receptors.

Alternative names

PDGF-R-beta, PDGFR-beta, PDGFR-1

Detailed product information

Technical specifications

CloneREA634
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD140b
Alternative names of antigenPDGF-R-beta, PDGFR-beta, PDGFR-1
Molecular mass of antigen [kDa]120
Distribution of antigenother
Entrez Gene ID18596
RRIDAB_2802019, AB_2857777, AB_2655098, AB_2655099, AB_2904726, AB_2733095

Resources for CD140b Antibody, anti-mouse, REAfinity™

Certificates

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References for CD140b Antibody, anti-mouse, REAfinity™

Publications

  1. Seifert, R. A. et al. (1993) PDGF-AB requires PDGF receptor alpha-subunits for high-affinity, but not for low-affinity, binding and signal transduction. J. Biol. Chem. 268(6): 4473-4480
  2. Tallquist, M. D. et al. (2003) Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development. PLoS Biol. 1(2): E52
  3. Taneda, S. et al. (2003) Obstructive uropathy in mice and humans: potential role for PDGF-D in the progression of tubulointerstitial injury. J. Am. Soc. Nephrol. 14(10): 2544-2555

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