CD45 antibodies, human

Clone: REA747 | Dilution: 1:50
Clone REA747 recognizes the human CD45 antigen, a member of the protein tyrosine phosphatase (PTP) family, also known as the leukocyte common antigen (LCA). The CD45 molecule is a type I transmembrane protein which is required for T and B cell activation and involved in cell growth, differentiation, mitotic cycle, and oncogenic transformation. CD45 is expressed in different isoforms (CD45RA, CD45RB, CD45RC, CD45RAB, CD45RAC, CD45RBC, CD45RO, CD45R (ABC)) depending on the differentiation status of the cell. The CD45 antibody recognizes a common epitope of all CD45 isoforms.
Additional information: Clone REA747 displays negligible binding to Fc receptors.

Alternative names

Ptprc, GP180, L-CA, LY5, T200

Technical specifications

  • Antigen: CD45
  • Clone: REA747
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Ptprc, GP180, L-CA, LY5, T200
  • Entrez Gene ID: 5788
  • Molecular mass of antigen [kDa]: 145
  • Distribution of antigen: B cells, basophils, dendritic cells, granulocytes, hematopoietic stem cells, Langerhans cells, leukocytes, lymphocytes, macrophages, mast cells, monocytes, plasma cells, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, VioBright 667, Biotin
  • Selected references

    1. Ralph, S. J. et al. (1987) Structural variants of human T200 glycoprotein (leukocyte-common antigen). EMBO J. 6(5): 1251-1257
    2. Vykoukal, J. et al. (2008) Enrichment of putative stem cells from adipose tissue using dielectrophoretic field-flow fractionation. Lab Chip 8(8): 1386-1393
    3. Kurian, L. et al. (2013) Conversion of human fibroblasts to angioblast-like progenitor cells. Nat. Methods 10(1): 77-83
Product options: 25
130-110-769

CD45-FITC, human

for 30
tests
(1)
EUR 80,00 
130-110-631

CD45-FITC, human

for 100
tests
(1)
EUR 195,00 
130-114-569

CD45-FITC, human

for 500
tests
(1)
EUR 485,00 
130-110-770

CD45-PE, human

for 30
tests
(1)
EUR 105,00 
130-110-632

CD45-PE, human

for 100
tests
(1)
EUR 260,00 
130-110-771

CD45-APC, human

for 30
tests
(1)
EUR 105,00 
130-110-633

CD45-APC, human

for 100
tests
(1)
EUR 260,00 
for 30
tests
(1)
EUR 130,00 
for 100
tests
(1)
EUR 305,00 
for 30
tests
(1)
EUR 130,00 
for 100
tests
(1)
EUR 305,00 
for 30
tests
(1)
EUR 135,00 
for 100
tests
(1)
EUR 315,00 
for 30
tests
(1)
EUR 135,00 
for 100
tests
(1)
EUR 315,00 
for 30
tests
(1)
EUR 135,00 
for 100
tests
(1)
EUR 315,00 
for 30
tests
(1)
EUR 135,00 
for 100
tests
(1)
EUR 315,00 
for 30
tests
(1)
EUR 170,00 
for 100
tests
(1)
EUR 400,00 
for 30
tests
(1)
EUR 170,00 
for 100
tests
(1)
EUR 400,00 
for 30
tests
(1)
EUR 80,00 
for 100
tests
(1)
EUR 195,00 

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