CD231 (TALLA) antibodies, human

CD231 (TALLA) antibodies, human

Clone: SN1a | Dilution: 1:11
The monoclonal antibody SN1a reacts with the 150 kDa glycoprotein CD231 also known as T cell–acute lymphoblastic leukemia specific antigen (TALLA), which is a member of the tetraspanin family. CD231 is expressed on T cell–type acute lymphoblastic leukemia (T-ALL) cells, skeletal muscle cells, brain, and spleen. It is reported that TALLA plays a role in integrin-mediated migration and can associate with phosphoinositide 4-kinase.

Alternative names

TSPAN7, A15, CCG-B7, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2, TM4SF2b

Technical specifications

  • Antigen: CD231 (TALLA)
  • Clone: SN1a
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: TSPAN7, A15, CCG-B7, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2, TM4SF2b
  • Entrez Gene ID: 7102
  • Molecular mass of antigen [kDa]: 28
  • Distribution of antigen: brain, endothelial cells, leukemia cells, neurons, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC, Biotin, PE
  • Selected references

    1. Hara, H. et al. (1987)
      Complete suppression of
      in vivo
      growth of human leukemia cells by specific immunotoxins: nude mouse models.
      Proc. Natl. Acad. Sci. U.S.A. 84: 3390-3394
    2. Seon, B. K. et al. (1983) Monoclonal antibody that defines a unique human T-cell leukemia antigen. Proc. Natl. Acad. Sci. U.S.A. 80: 845-849
    3. Matsuzaki, H. et al. (1987) Molecular nature of a cell membrane antigen specific for human T-cell acute lymphoblastic leukemia. Cancer Res. 47: 4283-4286
    4. Yauch, R. L. et al. (2000) Specific interactions among transmembrane 4 superfamily (TM4SF) proteins and phosphoinositide 4-kinase. Biochem. J. 351: 629-637
    5. Takagi, S. et al. (1995) Identification of a highly specific surface marker of T-cell acute lymphoblastic leukemia and neuroblastoma as a new member of the transmembrane 4 superfamily. Int. J. Cancer 61(5): 706-715
Product options: 3
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EUR 250,00 

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