Clone:
REA707
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
GPR5, mXCR1, CCXCR1, SCM1 receptor, XC chemokine receptor, Lymphotactin receptor

Specifications for XCR1 Antibody, anti-mouse/rat, REAfinity™

Overview

Clone REA707 recognizes the rat and mouse XCR1 antigen, also known as GPR5. XCR1 is a G protein–coupled chemokine receptor for XCL1 and XCL2, also known as lymphotactin-1 and -2. XCR1 is highly expressed in CD8α
+
dendritic cells. It plays a role in signal transduction by increasing the intracellular calcium ions level.
Additional information: Clone REA707 displays negligible binding to Fc receptors.

Alternative names

GPR5, mXCR1, CCXCR1, SCM1 receptor, XC chemokine receptor, Lymphotactin receptor

Detailed product information

Technical specifications

CloneREA707
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse, rat
AntigenXCR1
Alternative names of antigenGPR5, mXCR1, CCXCR1, SCM1 receptor, XC chemokine receptor, Lymphotactin receptor
Molecular mass of antigen [kDa]37, 39(separately shown for mouse and rat)
Distribution of antigendendritic cells
Entrez Gene ID23832, 301086
RRIDAB_2654281, AB_2654282, AB_2654283, AB_2654284, AB_2654285, AB_2654286, AB_2654287, AB_2654288, AB_2654289, AB_2654290, AB_2654291, AB_2654292, AB_2654293, AB_2654294, AB_2654295, AB_2654280

References for XCR1 Antibody, anti-mouse/rat, REAfinity™

Publications

  1. Yoshida, T. et al. (1998) Identification of single C motif-1/lymphotactin receptor XCR1. J. Biol. Chem. 273(26): 16551-16554
  2. Crozat, K. et al. (2011)
    Cutting edge: expression of XCR1 defines mouse lymphoid-tissue resident and migratory dendritic cells of the CD8α
    +
    type.
    J. Immunol. 187(9): 4411-4415
  3. Yamazaki, C. et al. (2013) Critical roles of a dendritic cell subset expressing a chemokine receptor, XCR1. J. Immunol. 190(12): 6071-6082

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