Clone:
REA1144
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
MICS, IF, IHC
Alternative names:
Vesicular glutamate transporter 2, DNPI, VGLUT2, Vimentin-Glut2, SLC17A6

Specifications for VGLUT2 Antibody, anti-human/mouse/rat, REAfinity™

Overview

Clone REA1144 recognizes the human, mouse and rat VGLUT2, a glutamate transporter, also known as DNPI, Vimentin-Glut2 or SLC17A6. Glutamate transporters belong to a family of neurotransmitter transporter proteins which consists of two classes, EAAT (excitatory amino acid transportesr) and VGLUT (vesicular glutamate transporters). VGLUTs are located in the membrane of glutamate-containing synaptic vesicles and regulate the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells.
Additional information: Clone REA1144 displays negligible binding to Fc receptors.

Alternative names

Vesicular glutamate transporter 2, DNPI, VGLUT2, Vimentin-Glut2, SLC17A6

Detailed product information

Technical specifications

CloneREA1144
Clonalitymonoclonal
Isotyperecombinant human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, mouse, rat
AntigenVGLUT2
Alternative names of antigenVesicular glutamate transporter 2, DNPI, VGLUT2, Vimentin-Glut2, SLC17A6
Molecular mass of antigen [kDa]64, 65(separately shown for human and mouse/rat)
Entrez Gene ID57084, 140919, 84487
RRIDAB_2857496, AB_2857495

References for VGLUT2 Antibody, anti-human/mouse/rat, REAfinity™

Publications

  1. Takamori, S. et al. (2001) Identification of differentiation-associated brain-specific phosphate transporter as a second vesicular glutamate transporter (VGLUT2). Neurosci. Lett. 21(22): 182-182
  2. Shigeri, Y. et al. (2004) Molecular pharmacology of glutamate transporters, EAATs and VGLUTs. Brain Res. Rev. 45(3): 250-265