Type of antibody:
Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Alternative names:
hTom22, 1C9-2, Tomm22

Specifications for TOM22 Antibody, anti-human, REAdye_lease™


Clone REAL439 is an antibody fragment derived from the full TOM22 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL439 recognizes the mitochondrial import receptor subunit TOM22 homolog antigen, a single-pass membrane protein which is also known as translocase of outer membrane 22 kDa subunit homolog. TOM22 is a central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. It functions together with the peripheral receptor TOM20 as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Alternative names

hTom22, 1C9-2, Tomm22

Detailed product information

Technical specifications

Isotype controlControl Antibody
Hostcell line
Type of antibodyReleasable fluorochromes, Primary antibodies, Recombinant antibodies
Alternative names of antigenhTom22, 1C9-2, Tomm22
Distribution of antigenubiquitous, ovarian cancer

Resources for TOM22 Antibody, anti-human, REAdye_lease™


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References for TOM22 Antibody, anti-human, REAdye_lease™


  1. Shiota, T. et al. (2011)
    In vivo
    protein-interaction mapping of a mitochondrial translocator protein Tom22 at work.
    Proc. Natl. Acad. Sci. U.S.A. 108(37): 15179-15183
  2. Bellot, G. et al. (2007) TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax. Cell Death Differ. 14(4): 785-794
  3. Yano, M. et al. (2000) Identification and functional analysis of human Tom22 for protein import into mitochondria. Mol. Cell. Biol. 20(19): 7205-7213

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