Clone:
1C9-2
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1
Applications:
ICFC, MICS, IF, IHC
Alternative names:
Tomm22, 1C9-2, MST065, MSTP065, hTom22

Specifications for TOM22 Antibody, anti-human/mouse

Overview

Clone 1C9-2 recognizes the human and mouse mitochondrial import receptor subunit TOM22 homolog antigen, a single-pass membrane protein, which is also known as translocase of outer membrane 22 kDa subunit homolog. TOM22 is a central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. It functions together with the peripheral receptor TOM20 as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore.

Alternative names

Tomm22, 1C9-2, MST065, MSTP065, hTom22

Detailed product information

Technical specifications

Clone1C9-2
Clonalitymonoclonal
Isotypemouse IgG1
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman, mouse, non-human primate
AntigenTOM22
Alternative names of antigenTomm22, 1C9-2, MST065, MSTP065, hTom22
Molecular mass of antigen [kDa]15(same molecular weight for human and mouse/rat)
Distribution of antigenother
Entrez Gene ID56993, 223696, 300075
RRIDAB_2857675, AB_2857693, AB_2857681, AB_2857698, AB_2857686, AB_2857687

References for TOM22 Antibody, anti-human/mouse

Publications

  1. Shiota, T. et al. (2011)
    In vivo
    protein-interaction mapping of a mitochondrial translocator protein Tom22 at work.
    Proc. Natl. Acad. Sci. U.S.A. 108(37): 15179-15183
  2. Bellot, G. et al. (2007) TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax. Cell Death Differ. 14(4): 785-794
  3. Yano. M. et al. (2000) Identification and functional analysis of human Tom22 for protein import into mitochondria. Mol. Cell. Biol. 20(19): 7205-7213

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TOM22 Antibody, anti-human/mouse

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