Clone:
REA684
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC

Specifications for TCR Vβ8 Antibody, anti-mouse, REAfinity™

Overview

Clone REA684 recognizes the mouse Vβ8 T cell receptor (TCR Vβ8) of mice having the b haplotype. Vβ8 is a variant of the TCR β chain that associates with the TCR α chain. The TCR is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. TCR Vβ8 is expressed on a subset of α/β T cells.
Additional information: Clone RE684 displays negligible binding to Fc receptors.

Detailed product information

Technical specifications

CloneREA684
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenTCR Vβ8
Distribution of antigenT cells
Entrez Gene ID100124664
RRIDAB_2653902, AB_2653903, AB_2653904, AB_2653905, AB_2653906, AB_2653907, AB_2653908, AB_2653909, AB_2653910, AB_2653911, AB_2653912, AB_2653901

References for TCR Vβ8 Antibody, anti-mouse, REAfinity™

Publications

  1. Haskins, K. et al. (1984) The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype. J. Exp. Med. 160(2): 452-471
  2. White, J. et al. (1989) The V beta-specific superantigen staphylococcal enterotoxin B: stimulation of mature T cells and clonal deletion in neonatal mice. Cell 56(1): 27-35
  3. Jiang, Y. et al. (1996)
    In vitro
    effects of HgCl
    2
    on murine lymphocytes. II. Selective activation of T cells expressing certain V beta TCR.
    Int. Immunol. 8(11): 1729-1736

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