Clone:
REA642
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
TCR Vb2, Gm16752, Tcrb-V4

Specifications for TCR Vβ2 Antibody, anti-mouse, REAfinity™

Overview

Clone REA642 recognizes the mouse V beta 2 T cell receptor (TCR Vβ2). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments.
Additional information: Clone REA642 displays negligible binding to Fc receptors.

Alternative names

TCR Vb2, Gm16752, Tcrb-V4

Detailed product information

Technical specifications

CloneREA642
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenTCR Vβ2
Alternative names of antigenTCR Vb2, Gm16752, Tcrb-V4
Molecular mass of antigen [kDa]11
Distribution of antigenT cells
Entrez Gene ID100124659
RRIDAB_2653825, AB_2653826, AB_2653827, AB_2653828, AB_2653829, AB_2653830, AB_2653831, AB_2653832, AB_2653833, AB_2653824

References for TCR Vβ2 Antibody, anti-mouse, REAfinity™

Publications

  1. Wu, Y. et al. (2007) Anti-idiotypic regulatory responses induced by vaccination with DNA encoding murine TCR Valpha5 and Vbeta2. Cell. Mol. Immunol. 4(4): 287-293
  2. Marrero, I. et al. (2013)
    High-throughput sequencing of islet-infiltrating memory CD4
    +
    T cells reveals a similar pattern of TCR Vβ usage in prediabetic and diabetic NOD mice.
    PLoS One 8(10): 76546
  3. Shirai, K. et al. (2015) Qualitative differences in brain-infiltrating T cells are associated with a fatal outcome in mice infected with Japanese encephalitis virus. Arch. Virol. 160(3): 765-775

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