Clone:
REA1121
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
MICS, IF, IHC
Alternative names:
SYP

Specifications for Synaptophysin Antibody, anti-human, REAfinity™

Overview

Clone REA1121 recognizes the human Synaptophysin, an integral membrane glycoprotein also known as major synaptic vesicle protein p38.
Synaptophysin plays a role in the regulation of short-term and long-term synaptic plasticity and is involved in structural functions. It is detected in neuroendocrine cells and in neurons, which are involved in in synaptic transmission. Furthermore Synaptophysin is used as a tumor marker for different tumors which emerge from neural and neuroendocrine tissues.
Additional information: Clone REA1121 displays negligible binding to Fc receptors.

Alternative names

SYP

Detailed product information

Technical specifications

CloneREA1121
Clonalitymonoclonal
Isotyperecombinant human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenSynaptophysin
Alternative names of antigenSYP
Molecular mass of antigen [kDa]34
Entrez Gene ID6855
RRIDAB_2857446, AB_2857447, AB_2857445

References for Synaptophysin Antibody, anti-human, REAfinity™

Publications

  1. Wiedenmann, B. et al. (1986) Synaptophysin: a marker protein for neuroendocrine cells and neoplasms. Proc. Natl. Acad. Sci. U.S.A. 83(10): 3500-3504
  2. Gould, V. E. et al. (1987) Synaptophysin expression in neuroendocrine neoplasms as determined by immunocytochemistry. Am. J. Pathol. 126(2): 243-257