Clone:
REA1125
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
MICS, IF, IHC
Alternative names:
Synapsin 1, Synapsin I, Syn1, SYN-1

Specifications for Synapsin-1 Antibody, anti-human/mouse/rat, REAfinity™

Overview

Clone REA1125 recognizes the human, mouse and rat neuron- specific phoshoprotein Synapsin-1. Synapsins are substrates for different protein kinases and involved in the regulation of neurotransmitter release. Synapsin I occurs in two isoforms (Synapsin Ia and Synapsin Ib) and belongs to the most specific markers of synapses throughout the central and peripheral nervous system.
Additional information: Clone REA1125 displays negligible binding to Fc receptors.

Alternative names

Synapsin 1, Synapsin I, Syn1, SYN-1

Detailed product information

Technical specifications

CloneREA1125
Clonalitymonoclonal
Isotyperecombinant human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, mouse, rat
AntigenSynapsin-1
Alternative names of antigenSynapsin 1, Synapsin I, Syn1, SYN-1
Molecular mass of antigen [kDa]74(same molecular weight for human and mouse/rat)
Entrez Gene ID6853, 20964, 24949
RRIDAB_2857455, AB_2857456, AB_2857454

References for Synapsin-1 Antibody, anti-human/mouse/rat, REAfinity™

Publications

  1. Huttner, W. B. et al. (1983) Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation. J. Cell Biol. 96(5): 1374-1388
  2. Südhof, T. C. et al. (1989) Synapsins: mosaics of shared and individual domains in a family of synaptic vesicle phosphoproteins. Science 245(4925): 1474-1480

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