Clone:
REA798
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
SIGLECF, SIGLEC5, mSiglec-F, Siglec-5

Specifications for Siglec-F Antibody, anti-mouse, REAfinity™

Overview

Clone REA798 recognizes the mouse siglec-F antigen, also kown as Siglec-5, which belongs to the siglec family (sialic acid-binding immunoglobulin-type lectins). Siglecs are expressed on immune cells and are a subset of the I-type lectins. Siglec-F contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. In mouse, siglec-F is an inhibitory receptor on eosinophils.
Additional information: Clone REA798 displays negligible binding to Fc receptors.

Alternative names

SIGLECF, SIGLEC5, mSiglec-F, Siglec-5

Detailed product information

Technical specifications

CloneREA798
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenSiglec-F
Alternative names of antigenSIGLECF, SIGLEC5, mSiglec-F, Siglec-5
Molecular mass of antigen [kDa]60
Entrez Gene ID233168
RRIDAB_2653438, AB_2653439, AB_2653440, AB_2653441, AB_2653442, AB_2653443, AB_2653444, AB_2653445, AB_2653446, AB_2653447, AB_2653448, AB_2653449, AB_2653450, AB_2653437

References for Siglec-F Antibody, anti-mouse, REAfinity™

Publications

  1. Tateno, H. et al. (2005) Mouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6-sulfo-sialyl Lewis X as a preferred glycan ligand. Glycobiology 15(11): 1125-1135
  2. Zhang, M. et al. (2007)
    Defining the
    in vivo
    function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophils.
    Blood 109(10): 4280-4287
  3. Guo, J. P. et al. (2011) Characterization of expression of glycan ligands for Siglec-F in normal mouse lungs. Am. J. Respir. Cell Mol. Biol. 44(2): 238-243

Related products for
Siglec-F Antibody, anti-mouse, REAfinity™

2 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?