Clone:
REA1061
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC, MC
Alternative names:
PRF1, FLH2, HPLH2, P1, PFN1, PFP

Specifications for Perforin Antibody, anti-human, REAfinity™

Overview

Clone REA1061 recognizes the human perforin, a 70 kDa cytolytic protein, which is expressed by cytotoxic T lymphocytes and natural killer (NK) cells, and which is stored in cytoplasmic granules. Upon cell activation perforin is released and functions as one of the major effector molecule to mediate killing of target cells.
Additional information: Clone REA1061 displays negligible binding to Fc receptors.

Alternative names

PRF1, FLH2, HPLH2, P1, PFN1, PFP

Detailed product information

Technical specifications

CloneREA1061
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (I), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenPerforin
Alternative names of antigenPRF1, FLH2, HPLH2, P1, PFN1, PFP
Molecular mass of antigen [kDa]59
Distribution of antigenNK cells, T cells
Entrez Gene ID5551
RRIDAB_2733687, AB_2733890, AB_2733891, AB_2733444, AB_2733445, AB_2733924, AB_2733925, AB_2733686

References for Perforin Antibody, anti-human, REAfinity™

Publications

  1. Voskoboinik, I. et al. (2015) Perforin and granzymes: function, dysfunction and human pathology. Nat. Rev. Immunol. 15(6): 388-400

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Perforin Antibody, anti-human, REAfinity™

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