Clone:
REA1126
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
MICS, IF, IHC
Alternative names:
Parvalbumin alpha, PVALB

Specifications for Parvalbumin Antibody, anti-human/mouse/rat, REAfinity™

Overview

Clone REA1126 recognizes the human, mouse and rat Parvalbumin, a calcium-binding albumin protein, which plays a role in calcium signaling and in different of physiological processes e.g. cell-cycle regulation, second messenger production, muscle contraction, microtubule organization and vision. Parvalbumin is detected in neostriatal GABAergic neurons, Purkinje cells, stellate and basket cells.
Additional information: Clone REA1126 displays negligible binding to Fc receptors.

Alternative names

Parvalbumin alpha, PVALB

Detailed product information

Technical specifications

CloneREA1126
Clonalitymonoclonal
Isotyperecombinant human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, mouse, rat
AntigenParvalbumin
Alternative names of antigenParvalbumin alpha, PVALB
Molecular mass of antigen [kDa]12(same molecular weight for human and mouse/rat)
Distribution of antigenneurons, other
Entrez Gene ID5816, 19293, 25269
RRIDAB_2857473, AB_2857472

References for Parvalbumin Antibody, anti-human/mouse/rat, REAfinity™

Publications

  1. Cowan, R. L. et al. (1990) Parvalbumin-containing GABAergic interneurons in the rat neostriatum. J. Comp. Neurol. 302(2): 197-205
  2. Cates, M.S. et al. (1999) Metal-ion affinity and specificity in EF-hand proteins: coordination geometry and domain plasticity in parvalbumin. Structure 7(10): 1269-1278
  3. Schwaller, B. et al. (2002) 'New' functions for 'old' proteins: the role of the calcium-binding proteins calbindin D-28k, calretinin and parvalbumin, in cerebellar physiology. Studies with knockout mice. Cerebellum 1(4): 541-258

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