NiraWave M is a micellar near-infrared (NIR) fluorescence contrast agent exhibiting a prolonged blood circulation and high quantum yield specifically formulated for pre-clinical optical imaging.
NiraWave M shows absorption and emission (fluorescence) in the NIR spectral range allowing an increased tissue penetration.
Due to the micellar formulation of indocyanine green, NiraWave M exhibits a stronger fluorescence, higher aqueous stability and prolonged blood circulation.
NiraWave M is excreted by the liver within hours.

Data and images for NiraWave M

Figures

Figure 1

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Normalized absorption and emission spectra of NiraWave™ M in plasma.

Figure 1

Normalized absorption and emission spectra of NiraWave™ M in plasma.

Specifications for NiraWave M

Overview

NiraWave M is a micellar near-infrared (NIR) fluorescence contrast agent exhibiting a prolonged blood circulation and high quantum yield specifically formulated for pre-clinical optical imaging.
NiraWave M shows absorption and emission (fluorescence) in the NIR spectral range allowing an increased tissue penetration.
Due to the micellar formulation of indocyanine green, NiraWave M exhibits a stronger fluorescence, higher aqueous stability and prolonged blood circulation.
NiraWave M is excreted by the liver within hours.

Detailed product information

Applications

NiraWave M is indicated for use in optical imaging of small animals, for example mice, to facilitate the visualization of the vasculature. Examples include fluorescence angiography and fenestration of blood vessels in inflamed tissue or tumors.

References for NiraWave M

Publications

  1. Kirchherr, A. K. et al. (2009) Stabilization of indocyanine green by encapsulation within micellar systems. Mol. Pharm. 6: 480-491
  2. Kirchherr, A.K. (2010) Herstellung und Charakterisierung kolloidaler Formulierungen für Indocyaningrün als Kontrastmittel für die optische Bildgebung. : Doctoral thesis

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